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Research into trichotillomania, hair pulling, compulsive skin picking, OCDs, etc. is challenging for a number of reasons.  Regulations are different in different countries, and obtaining large enough groups of participants can be problematic.

Individuals have different levels of neuro-biochemistry, on-board bacterium, diet and lifestyle, so standard treatment programs without a primary carer do not work for many.

Practitioner-based ACT or Acceptance and Commitment Therapy shows the best long-term results and specialist trichotillomania and BFRB appointments are available here.

Body Focused Repetitive Behaviors (BFRBs) are categorised under Obsessive Compulsive Related Disorders in DSM-5 (The Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition). BFRBs can be passive activities, experienced particularly during periods of relaxation and/or boredom.

Researchers have studied specific nutritional supplements to prevent skin picking and hair pulling. Specific supplements include NAC (N-acetylcysteine), magnesium and glutathione, all of which show some improvement in BFRBs.

  • A full nutritional program should be tailored to the individual by qualified personnel. Make an appointment.

The role of enhanced emotion in trichotillomania is evident in certain brain areas, and the reward centre of the brain reveals a connection with dopamine. An MRI-based human study by Grachev investigated only twenty right-handed females aged 28-30, ten were tricsters while ten were not. Two areas of the neocortex were significantly reduced in volume, but there was no overall loss of volume, indicating that the tricsters’ brains may have developed differently, possibly in a compensatory manner. Additional studies have also revealed increased grey matter in the amygdale hippocampus area of the brain, which plays a vast role in emotional processing (Aldridge et al, 1993).

Increased cortical thickness has also recently been revealed in people with trichotillomania and their close relatives, possibly causing response inhibition. (Odlaug et al, 2014)


Aldridge JW,. Berridge KC, Herman M, Zimmer L, Research report neuronal coding, Psychological Sciences, 4 (1993).

Christenson GA, Popkin MK, Mackenzie TB & Realmuto GM, Lithium treatment of chronic hairpulling, Journal of Clinical Psychiatry, 52 (1991).

Grachev ID, MRI-based morphometric topographic parcellation of human neocortex in trichotillomania, Psychiatry and Clinical Neuroscience, 51(1997).

Odlaug BL, Chamberlain SR, Derbyshire KL, Leppink EW, Grant JE, Impaired response inhibition and excess cortical thickness as candidate endophenotypes for trichotillomania, Journal of Psychiatric Research, 59 (2014).

If you are interested in carrying out a research project and would like any help or involvement from us; please contact us. We are always happy to help improve knowledge of trichotillomania in any way we can.

Published 24 November 2020, review 24 November 2021